| Synonyms | adrenocorticotropic hormone; acth; corticotropin |
| Sequence | Human: H-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro-OH or H-SYSMEHFRWGKPVGKKRRPVKVYP-OH |
| Molecular Formula | C136H210N40O31S |
| Molecular Weight | 2933.5 g/mol |
| Purity | Purity > 95% by HPLC |
| Format | Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt. |
| Solubility | Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile. |
| Storage | Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C. |
| description | adrenocorticotropic hormone (acth), also known as corticotropin, is produced and secreted by the anterior pituitary gland. acth is an important component of the hypothalamic-pituitary-adrenal axis as a response to biological stress. acth secretion is triggered by the corticotropin-releasing hormone (crh) released from the hypothalamus, and stimulates the adrenal glands to release corticosteroids such as cortisol. acth [1-39] corresponds to full-length acth. acth [1-24] is conserved across species and is 75% as potent as acth. acth [1-10] has no acth activity but alter blood pressure. acth [4-10] has neurological effects. |
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