| Synonyms | |
| Sequence | The synthetic peptide used to raise the antibody Cat. No. 250885 is selected from a sequence within the C-term region of human TIMP-3. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended. |
| Molecular Formula | C62H84N16O18S1 |
| Molecular Weight | 1373.5 g/mol |
| Purity | Purity > 80% by HPLC |
| Format | Each vial contains 0.1 ml peptide in deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect. |
| Solubility | Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile. |
| Storage | Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. |
| description | tissue inhibitor of metalloproteinases 3 (timp-3) binds to metalloproteinases such as collagenases and irreversibly inactivates the proteases. timp-2 is involved in the extracellular matrix remodeling by binding to mmp-1, -2, -3, -7, -9, -13, -14 and -15. defects in timp-3 are the cause of sorsby fundus dystrophy (sfd), a macular disorder leading to vision loss. |
How to place a order：
1) Contact us at: Service@apichina.com ;2) Provide us peptides information including Sequence, Purity, Quantity and modification(If necessary, we agree to sign confidential agreement with you before you provide these information), we will make you a quotes within 30 minutes;
3) Place us a purchaser order, we can send you a sales contract too if you need;
4) Start synthesis, and we will inform you the updates of synthesis in time;
5) Arrange shippment, HPLC analysis, MS spectrum will be shipped along the peptides too;
6) Refund all pre-payment(if pre-pay us) if we failed to synthesize any of them;
7) After-sale service: Contact us anytime if you have any problem when you use the peptides, and we will reply you as soon as possible.