| Synonyms | |
| Sequence | Human: H-Ser-Phe-Leu-Leu-Arg-Asn-Pro-Asn-Asp-Lys-Tyr-Glu-Pro-Phe-OH or H-SFLLRNPNDKYEPF-OH |
| Molecular Formula | C81H118N20O23 |
| Molecular Weight | 1739.96 g/mol |
| Purity | Purity > 95% by HPLC |
| Format | Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt. |
| Solubility | Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile. |
| Storage | Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C. |
| description | thrombin signaling of platelets is mediated by a g protein-coupled protease-activated receptor (par). the par is activated after thrombin binding and subsequent cleavage of the amino terminal end of the receptor. this new amino terminus acts as a tethered ligand and binds intramolecularly to the body of the par, resulting in a transmembrane signal. a synthetic thrombin receptor agonist peptide (trp) of 6 residues (sfllrn) corresponding to aa42-47 of the thrombin receptor was found to be as effective as thrombin for ca2+ mobilization. trap can be used instead of thrombin to trigger platelet aggregation and clot retraction. |
How to place a order：
1) Contact us at: Service@apichina.com ;2) Provide us peptides information including Sequence, Purity, Quantity and modification(If necessary, we agree to sign confidential agreement with you before you provide these information), we will make you a quotes within 30 minutes;
3) Place us a purchaser order, we can send you a sales contract too if you need;
4) Start synthesis, and we will inform you the updates of synthesis in time;
5) Arrange shippment, HPLC analysis, MS spectrum will be shipped along the peptides too;
6) Refund all pre-payment(if pre-pay us) if we failed to synthesize any of them;
7) After-sale service: Contact us anytime if you have any problem when you use the peptides, and we will reply you as soon as possible.