| Synonyms | |
| Sequence | Human: H-Val-Pro-Asn-Leu-Pro-Gln-Arg-Phe-NH2 or H-VPNLPQRF-NH2 |
| Molecular Formula | C45H72N14O10 |
| Molecular Weight | 969.1 g/mol |
| Purity | Purity > 95% by HPLC |
| Format | Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt. |
| Solubility | Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile. |
| Storage | Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C. |
| description | rfamide-related peptides (rfrp-1 and rfrp-3) belong to a group of rfamide peptides, which have an arginine-phenylalanine-amide structure at the c-term end. rfrps share a similar c-term sequence with neuropeptide ff (npff) and have a relatively high affinity to gpr147 (also called npff1 receptor, rfrp receptor or ot7t022). rfrp-1 facilitates prolactin release from the pituitary and attenuates morphine-induced analgesia. rfrp-3 inhibits the gonadotrophin-releasing hormone neuron-luteinising hormone system in mammals and increases food intake. rfrp-1 and rfrp-3 are derived from the same preprotein (pro-fmrfamide-related neuropeptide vf) and are co-expressed in single neurons in the dorsomedial hypothalamus, which plays a pivotal role in the control of stress responses in neuroendocrine, autonomic and behavioral systems. rfrp-3 inhibits forskolin-stimulated camp production in cho cells expressing ot7t022 (ed50=0.7 nm). |
How to place a order：
1) Contact us at: Service@apichina.com ;2) Provide us peptides information including Sequence, Purity, Quantity and modification(If necessary, we agree to sign confidential agreement with you before you provide these information), we will make you a quotes within 30 minutes;
3) Place us a purchaser order, we can send you a sales contract too if you need;
4) Start synthesis, and we will inform you the updates of synthesis in time;
5) Arrange shippment, HPLC analysis, MS spectrum will be shipped along the peptides too;
6) Refund all pre-payment(if pre-pay us) if we failed to synthesize any of them;
7) After-sale service: Contact us anytime if you have any problem when you use the peptides, and we will reply you as soon as possible.