| Synonyms | |
| Sequence | The synthetic peptide used to raise the antibody Cat. No. 200145 is selected from a sequence within the N-term region of human PTEN. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended. |
| Molecular Formula | C94H151N31O31S1 |
| Molecular Weight | 2243.4 g/mol |
| Purity | Purity > 80% by HPLC |
| Format | Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking e |
| Solubility | Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile. |
| Storage | Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. |
| description | pten is a dual-specificity protein phosphatase, dephosphorylating tyrosine-, threonine- and serine-phosphorylated proteins. pten has also a lipid phosphatase activity that is critical for its tumor suppression function. pten antagonizes the pi3k-akt/pkb signaling pathway by dephosphorylating phosphoinositides and thereby modulating cell cycle progression and cell survival. defects in pten are the cause of numerous cancers such as in cowden disease (breast, thyroid and skin cancer predisposition), lhermitte-duclos disease, and head and neck squamous cell carcinoma. |
How to place a order：
1) Contact us at: Service@apichina.com ;2) Provide us peptides information including Sequence, Purity, Quantity and modification(If necessary, we agree to sign confidential agreement with you before you provide these information), we will make you a quotes within 30 minutes;
3) Place us a purchaser order, we can send you a sales contract too if you need;
4) Start synthesis, and we will inform you the updates of synthesis in time;
5) Arrange shippment, HPLC analysis, MS spectrum will be shipped along the peptides too;
6) Refund all pre-payment(if pre-pay us) if we failed to synthesize any of them;
7) After-sale service: Contact us anytime if you have any problem when you use the peptides, and we will reply you as soon as possible.