| Synonyms | |
| Sequence | Human: H-His-Ser-Leu-Gly-Lys-Trp-Leu-Gly-His-Pro-Asp-Lys-Phe-OH or H-HSLGKWLGHPDKF-OH |
| Molecular Formula | C72H104N20O17 |
| Molecular Weight | 1521.7 g/mol |
| Purity | Purity > 95% by HPLC |
| Format | Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt. |
| Solubility | Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile. |
| Storage | Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C. |
| description | the plp [139-151] peptide from the myelin proteolipid protein (plp) has been found to be highly immunogenic in inducing experimental allergic encephalomyelitis (eae) in sjc/j (h-2s) mice as part of an autoimmune response. the sequence is derived from plp with a cysteine residue replaced by a serine. the peptide is conserved in mouse, rat, monkey, dog, pig, bovine and found to be similar in chicken, frog, turtle except for the first two residues. mouse t-cell clones that are reactive with the peptide have been developped, and variations on the different clones' ability to elicit the immune response have been used to understand mechanisms of t-cell function. later work has devised analogs of this peptide that block the immune response in vitro and in vivo, with implications for the regulation of autoimmune diseases. |
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1) Contact us at: Service@apichina.com ;2) Provide us peptides information including Sequence, Purity, Quantity and modification(If necessary, we agree to sign confidential agreement with you before you provide these information), we will make you a quotes within 30 minutes;
3) Place us a purchaser order, we can send you a sales contract too if you need;
4) Start synthesis, and we will inform you the updates of synthesis in time;
5) Arrange shippment, HPLC analysis, MS spectrum will be shipped along the peptides too;
6) Refund all pre-payment(if pre-pay us) if we failed to synthesize any of them;
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