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H-Ile-Phe-OH

A dipeptide able to self-associate in aqueous solution as a transparent, thermoreversible gel formed by a network of fibrillar nanostructures that exhibit strong birefringence upon Congo red binding. G-2420 and similar dipeptides may serve as models for studying the first steps of the aggregation/fibrillation of amyloid peptides.

CAS
22951-98-0
EINECS
Molecular Formula
C15H22N2O3
Molecular Weight
278.35
PubChem CID
MDL Number
MFCD00037253
Beilstein
Merck Index
GHS

Chemical Properties

Density 1.144±0.06 g/cm3(Predicted) Boiling point 501.2±50.0 °C(Predicted)
Melting point >249°C (dec.) Refractive index
Flash point Optical Activity
Water solubility Physical State
Purity Appearance
InChI InChI=1S/C15H22N2O3/c1-3-10(2)13(16)14(18)17-12(15(19)20)9-11-7-5-4-6-8-11/h4-8,10,12-13H,3,9,16H2,1-2H3,(H,17,18)(H,19,20)/t10-,12-,13-/m0/s1
InChIKey InChIKey=WMDZARSFSMZOQO-DRZSPHRISA-N
Synonyms Isoleucyl-Phenylalanine; L-Ile-L-Phe; L-Phenylalanine,L-isoleucyl-
SMILES O=C(O)C(NC(=O)C(N)C(C)CC)CC=1C=CC=CC1
Solubility data

Biological Description

IC50
Ki Data
pK Values 3.41±0.10(Predicted) Storage Store at -20°C
Sequence H2N-Ile-Phe-COOH
Sequence(single) H2N-IF-OH
In Vitro
In Vivo

Application

Application

Security information

Hazard Symbols
Risk Codes
Safety Description

References

References
Isoleucyl-Phenylalanine is a dipeptide derived from the incomplete breakdown of protein digestion or protein catabolism. It has not yet been identified in human tissues or biofluids and so it is classified as an ′Expected′ metabolite.
 
 

Image text
Peptide
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